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| Laboratory |
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The main goal of an ancient DNA (aDNA) facility is to avoid contamination with modern nucleic acids, as the aDNA conservation of prehistoric remains is reduced by enzymatic, hydrolytic and oxidative processes after death. This is especially true for the analysis of human samples, where the possibility of contamination by lab, museum, archaeological or anthropological staff is much higher than with animal samples.
Our work is carried out in two separate laboratories. The first, the ancient DNA facility (pre-PCR), comprises all procedures of sample preparation, DNA extraction and the set-up of PCR. The second lab (post-PCR) is a standard molecular genetics lab for gel electrophoresis and DNA sequencing including a cloning facility.
The strict separation of pre- and post- PCR is particularly important to prevent the transfer of modern DNA molecules from the post- to the pre- PCR lab. To prevent this contamination there is a spatial separation of the labs by locating them in two different buildings.
The aDNA laboratory is run in colaboration with the Molecular Archaeology Group |
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| Get to know the Mainz aDNA lab! |
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The cross section of the aDNA lab shows the rooms and the procedural sequence between them. For further information about each room please click on the relevant area in the map or open the following presentation!
aDNA lab Mainz
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Johannes Gutenberg University
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