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Nadine Mersmann, Dmitri Tkachev, Ruth Jelinek, Philipp Thomas Röth, Wiebke Möbius, Torben Ruhwedel, Sabine Rühle, Wolfgang Weber-Fahr, Alexander Sartorius, Matthias Klugmann (2011) Aspartoacylase-LacZ Knockin Mice: An Engineered Model of Canavan Disease. PLoS ONE 6(5): e20336. doi:10.1371/journal.pone.0020336
Schicho R, Bashashati M, Bawa M, McHugh D, Saur D, Hu HM, Zimmer A, Lutz B, Mackie K, Bradshaw HB, McCafferty DM, Sharkey KA, Storr M. (2011) The atypical cannabinoid O-1602 protects against experimental colitis and inhibits neutrophil recruitment. Inflamm Bowel Dis. 2010 Nov 15. [Epub ahead of print]
Argaw A, Duff G, Zabouri N, Cecyre B, Chaine N, Cherif H, Tea N, Lutz B, Ptito M, Bouchard JF (2011) Concerted Action of CB1 Cannabinoid Receptor and Deleted in Colorectal Cancer in Axon Guidance JOURNAL OF NEUROSCIENCE. 2011; 31 (4): 1489-1499 Article
Blazquez C, Chiarlone A, Sagredo O, Aguado T, Pazos MR, Resel E, Palazuelos J, Julien B, Salazar M, Borner C, Benito C, Carrasco C, Diez-Zaera M, Paoletti P, Diaz-Hernandez M, Ruiz C, Sendtner M, Lucas JJ, de Yebenes JG, Marsicano G, Monory K, Lutz B, Romero J, Alberch J, Gines S, Kraus J, Fernandez-Ruiz J, Galve-Roperh I, Guzman M (2011) Loss of striatal type 1 cannabinoid receptors is a key pathogenic factor in Huntington's disease BRAIN. 2011; 134: 119-136 Article
Carey MR, Myoga MH, McDaniels KR, Marsicano G, Lutz B, Mackie K, Regehr WG (2011) Presynaptic CB1 Receptors Regulate Synaptic Plasticity at Cerebellar Parallel Fiber Synapses JOURNAL OF NEUROPHYSIOLOGY. 2011; 105 (2): 958-963 Article
Kamprath K, Romo-Parra H, Haring M, Gaburro S, Doengi M, Lutz B, Pape HC (2011) Short-Term Adaptation of Conditioned Fear Responses Through Endocannabinoid Signaling in the Central Amygdala NEUROPSYCHOPHARMACOLOGY. 2011; 36 (3): 652-663 Article
Klugmann M, Klippenstein V, Leweke FM, Spanagel R, Schneider M (2011) Cannabinoid exposure in pubertal rats increases spontaneous ethanol consumption and NMDA receptor associated protein levels INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY. 2011; 14 (4): 505-517 Article
Valor LM, Pulopulos MM, Jimenez-Minchan M, Olivares R, Lutz B, Barco A (2011) Ablation of CBP in Forebrain Principal Neurons Causes Modest Memory and Transcriptional Defects and a Dramatic Reduction of Histone Acetylation But Does Not Affect Cell Viability JOURNAL OF NEUROSCIENCE. 2011; 31 (5): 1652-1663 Article
Garron T. Dodd, Giacomo Mancini, Beat Lutz and Simon M. Luckman (2010) The Peptide Hemopressin Acts through CB1 Cannabinoid Receptors to Reduce Food Intake in Rats and Mice. The Journal of Neuroscience, May 26, 2010 • 30(21):7369 –7376 • 7369
Lori A. Knackstedt, Khaled Moussawi, Ryan Lalumiere, Marek Schwendt, Matthias Klugmann and Peter W. Kalivas (2010) Extinction Training after Cocaine Self-Administration Induces Glutamatergic Plasticity to Inhibit Cocaine Seeking. The Journal of Neuroscience, June 9, 2010 • 30(23):7984 –7992
Federico Massa, Giacomo Mancini, Helmut Schmidt, Frauke Steindel, Ken Mackie, Carlo Angioni, Stephane H. R. Oliet, Gerd Geisslinger and Beat Lutz (2010) Alterations in the Hippocampal Endocannabinoid System in Diet-Induced Obese Mice. The Journal of Neuroscience, May 5, 2010 • 30(18):6273– 6281 • 6273
Elmar Porten, Beate Seliger, Verena A. Schneider, Stefan Wöll, Daniela Stangel, Rene Ramseger and Stephan Kröger (2010) The Process-inducing Activity of Transmembrane Agrin Requires Follistatin-like Domains. THE JOURNAL OF BIOLOGICAL CHEMISTRY VOL. 285, NO. 5: 3114–3125
Sodikdjon A. Kodirov, Julia Jasiewicz, Parisa Amirmahani, Dimitrios Psyrakis, Kathrin Bonni, Michael Wehrmeister and Beat Lutz (2010) Endogenous cannabinoids trigger the depolarization-induced suppression of excitation in the lateral amygdala. Downloaded from learnmem.cshlp.org on December 31, 2009 - Published by Cold Spring Harbor Laboratory Press
Andreas Rogalewski, Tanjew Dittgen, Matthias Klugmann, Friederike Kirsch, Carola Krüger, Claudia Pitzer, Jens Minnerup, Wolf-Rüdiger Schäbitz, Armin Schneider (2010) Semaphorin 6A Improves Functional Recovery in Conjunction with Motor Training after Cerebral Ischemia
Nina L. Cluny, Catherine M. Keenan, Marnie Duncan, Alyson Fox, Beat Lutz, and Keith A. Sharkey (2010) Naphthalen-1-yl-(4-pentyloxynaphthalen-1-yl)methanone (SAB378), a Peripherally Restricted Cannabinoid CB1/CB2 Receptor Agonist, Inhibits Gastrointestinal Motility but Has No Effect on Experimental Colitis in Mice. THE JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS Vol. 334, No. 3: 973–980
Chia-Shan Wu, Jie Zhu, Jim Wager-Miller, Shan Wang, Dennis O’Leary, Krisztina Monory, Beat Lutz, Ken Mackie and Hui-Chen Lu (2010) Requirement of cannabinoid CB1 receptors in cortical pyramidal neurons for appropriate development of corticothalamic and thalamocortical projections. European Journal of Neuroscience, Vol. 32, pp. 693–706
M. A. Storr, M. Bashashati, C. Hirota, V. K. Vemuri, C. M. Keenan, M. Duncan, B. Lutz, K. Mackie, A. Makriyannis, W. K. Macnaughton, K. A. Sharkey (2010) Differential effects of CB1 neutral antagonists and inverse agonists on gastrointestinal motility in mice. Neurogastroenterol Motil 22, 787–e223
NL Cluny, VK Vemuri, AP Chambers, CL Limebeer, H Bedard, JT Wood, B Lutz, A Zimmer, LA Parker, A Makriyannis and KA Sharkey (2010) A novel peripherally restricted cannabinoid receptor antagonist, AM6545, reduces food intake and body weight, but does not cause malaise, in rodents. British Journal of Pharmacology DOI:10.1111/j.1476-5381.2010.00908.x www.brjpharmacol.org
Guggenhuber S, Monory K, Lutz B, Klugmann M (2010) AAV Vector-Mediated Overexpression of CB1 Cannabinoid Receptor in Pyramidal Neurons of the Hippocampus Protects against Seizure-Induced Excitoxicity. PLoS ONE 5(12): e15707. doi:10.1371/journal.pone.0015707
Quarta C, Bellocchio L, Mancini G, Mazza R, Cervino C, Braulke LJ, Fekete C, Latorre R, Nanni C, Bucci M, Clemens LE, Heldmaier G, Watanabe M, Leste-Lassere T, Maitre M, Tedesco L, Fanelli F, Reuss S, Klaus S, Srivastava RK, Monory K, Valerio A, Grandis A, De Giorgio R, Pasquali R, Nisoli E, Cota D, Lutz B, Marsicano G, Pagotto U (2010) CB1 signaling in forebrain and sympathetic neurons is a key determinant of endocannabinoid actions on energy balance. Cell Metab 11:273-85.
Storr MA, Bashashati M, Hirota C, Vemuri VK, Keenan CM, Duncan M, Lutz B, Mackie K, Makriyannis A, Macnaughton WK, Sharkey KA (2010) Differential effects of CB1 neutral antagonists and inverse agonists on gastrointestinal motility in mice. Neurogastroenterol Motil. 2010 Feb 24. [Epub ahead of print]
Kodirov SA, Jasiewicz J, Amirmahani P, Psyrakis D, Bonni K, Wehrmeister M, Lutz B (2009) Endogenous cannabinoids trigger the depolarization-induced suppression of excitation in the lateral amygdala. Learn Mem 17:43-9.
Pernía-Andrade AJ, Kato A, Witschi R, Nyilas R, Katona I, Freund TF, Watanabe M, Filitz J, Koppert W, Schüttler J, Ji G, Neugebauer V, Marsicano G, Lutz B, Vanegas H, Zeilhofer HU (2009) Spinal endocannabinoids and CB1 receptors mediate C-fiber-induced heterosynaptic pain plasticity. Science 325:760-764.
Puighermanal E, Marsicano G, Busquets A, Lutz B, Maldonado R, Ozaita A (2009) Cannabinoid modulation of hippocampal long-term memory is mediated by mTOR signalling. Nat Neurosci 12:1152-1158.
Pilpel N, Landeck M, Klugmann M, Seeburg PH, Schwarz MK (2009) Rapid and long-lasting transduction of neurons by targeted recombinant virus injection into the neonatal mouse brain J Neurosci Meth 182:55-63
Cozzoli DK, Goulding SP, Zhang PW, Xiao B, Hu J-H, Ary AW, Obara I, Rahn, A, Abou-Ziab, H, Tyrrel B, Marini M, Yoneyama N, Metten P, Snelling C, Dehoff M, Crabbe J, Finn DA, Klugmann M, Worley PF, Szumlinski KK (2009) Binge drinking up-regulates accumbens mGluR5-Homer2-PI3K signaling: Functional implications for alcoholism J Neurosci 29:8655-68
Jacob W, Yassouridis A, Marsicano G, Monory K, Lutz B, Wotjak CT (2009) Endocannabinoids render exploratory behaviour largely independent of the test aversiveness: role of glutamatergic transmission. Genes Brain Behav 2009 May 29. [Epub ahead of print]
Lutz B (2009) From molecular neurodevelopment to psychiatry: new insights in mechanisms underlying Cannabis-induced psychosis and schizophrenia. Eur Arch Psychiatry Clin Neurosci 2009 Jul 2. [Epub ahead of print] (Review)
Price DA, Seillier A, Koek W, Acosta Y, Fernandez E, Strong JR, Lutz B, Marsicano G, Roberts JL, Guiffrida A (2009) WIN55,212-2, a cannabinoid receptor agonist, protects against nigrostriatal cell loss in the MPTP mouse model of Parkinson¹s Disease. Eur J Neurosci 29:2177-2186.
Chung SC, Hammarsten P, Josefsson A, Stattin P, Granfors T, Egevad L, Mancini G, Lutz B, Bergh A, Fowler CJ. (2009) A high cannabinoid CB1 receptor immunoreactivity is associated with disease severity and outcome in prostate cancer. Eur J Cancer 45:174-82.
Kamprath K, Plendl W, Marsicano G, Deussing JM, Wurst W, Lutz B, Wotjak CT (2009) Endocannabinoids mediate acute fear adaptation via glutamatergic neurons independently of CRH signaling. Genes Brain Behav 8:203-211.
Monory K, Lutz B (2009) Genetic models of the endocannabinoid system. In: Behavioral Neurobiology of the Endocannabinoid System. Eds. D.A. Kendall and S. Alexander. Current Topics in Behavioral Neurosciences (CTBN) book series. Springer Berlin-Heidelberg 2009. (Review)
Moreira FA, Grieb M, Lutz B (2009) Central side-effects of therapies based on CB1 cannabinoid receptor agonists and antagonists: focus on anxiety and depression. Best Practice & Research Clinical Endocrinology & Metabolism 23:133-144. (Review)
Lutz B. Endocannabinoid signals in the control of emotion (2009) Curr Opin Pharmacol 9:46-52. (Review)
Lutz B, Marsicano G (2009) Role of endocannabinoids in synaptic plasticity and memory. In Larry R. Squire, Editor-in-Chief, Encyclopedia of Neuroscience, Academic Press, Oxford, vol. 3, pp. 963-975. (Review)
Cluny NL, Keenan CM, Lutz B, Piomelli D, Sharkey KA (2009) The identification of peroxisome proliferator-activated receptor alpha independent effects of oleoylethanolamide on intestinal transit in mice. Neurogastroenterology and Motility 21:420-429.
Duncan M, Thomas AD, Cluny NL, Patel A, Patel KD, Lutz B, Piomelli D, Alexander SPH, Sharkey KA. The distribution and function of monoacylglycerol lipase in the gastrointestinal tract. Am J Physiol - Gastrointestinal and Liver Physiology 295(6):G1255-65.
Sitz JH, Baumgärtel K, Hämmerle B, Papadopoulos C, Hekerman P, Tejedor F, Becker W, Lutz B (2008) The Down syndrome candidate kinase DYRK1A phosphorylates the neurodegeneration-related septin SEPT4. Neuroscience 157:596-605.
Osei-Hyiaman D, Liu J, Zhou L, Godlewski G, Harvey-White J, Jeong Wi, Bátkai S, Marsicano G, Lutz B, Buettner C, Kunos G (2008) Hepatic CB1 receptor involvement in diet-induced steatosis, altered lipid profile, and insulin and leptin resistance. J Clin Invest 118:3160-3169.
Bilbao A, Rodriguez Parkitna J, Engblom D, Perreau-Lenz S, Sanchis-Segura C, Schneider M, Konopka W, Westphal M, Breen G, Desrivieres S, Klugmann M, Guindalini C, Vallada H, Laranjeira R, Rodriguez de Fonseca F, Schumann G, Schütz G, Spanagel R (2008) Loss of the Ca2+/calmodulin-dependent protein kinase type IV in dopaminoceptive neurons enhances behavioral effects of cocaine Proc Natl Acad Sci 105: 17549-54
Szumlinski KK, Ary AW, Lominac K, Klugmann M, Kippin, TE (2008) Accumbens Homer2 over-expression facilitates alcohol-induced neuroplasticity in C57BL/6J mice Neuropsychopharmacology 33:1365-78
Franich NR, Fitzsimons HL, Fong DM, Klugmann M, During MJ, Young D (2008) AAV vector-mediated RNAi of Mutant Huntingtin Expression is Neuroprotective in a Novel Genetic Rat Model of Huntington’s Disease Mol Ther 16:947-56
Steiner M, Marsicano G, Wotjak CT, Lutz B (2008) Conditional cannabinoid receptor type 1 mutants reveal neuron subpopulation-specific effects on behavioral and neuroendocrine stress responses. Psychoneuroendocrinology 33:1165-1170.
Hansen HH, Krutz B, Sifringer M, Stefovska V, Bittigau P, Pragst F, Marsicano G, Lutz B, Ikonomidou C (2008) Cannabinoids enhance susceptibility of immature brain to ethanol neurotoxicity. Ann Neurol 64:52-62.
Lutz B, Monory K (2008) Soothing the seizures of children. Nat Med 14:721-2. (Commentary)
Mulder J, Aguado T, Keimpema E, Barabás K, Ballester Rosado CJ, Nguyen L, Monory K, Marsicano G, Di Marzo V, Hurd YL, Guillemot F, Mackie K, Lutz B, Guzmán M, Lu HC, Galve-Roperh I, Harkany T. (2008) Endocannabinoid signaling controls pyramidal cell specification and long-range axon patterning. Proc Natl Acad Sci U S A 105:8760-5.
Storr MA, Keenan CM, Emmerdinger D, Zhang H, Yüce B, Sibaev A, Massa F, Buckley NE, Lutz B, Göke B, Brand S, Patel KD, Sharkey KA. (2008) Targeting endocannabinoid degradation protects against experimental colitis in mice: involvement of CB1 and CB2 receptors. J Mol Med 86:925-36.
Monory, K, Lutz, B (2008) The endocanabinoid system as a therapeutic target in epilepsy. In: Cannabinoids and the brain. Ed.: Attila Köfalvi. Springer.
Tedesco L, Valerio A, Cervino C, Cardile A, Pagano C, Vettor R, Pasquali R, Carruba MO, Marsicano G, Lutz B, Pagotto U, Nisoli E (2008) Cannabinoid type 1 receptor blockade promotes mitochondrial biogenesis through eNOS expression in white adipocytes. Diabetes. 2008 May 13. [Epub ahead of print]
Moreira FA, Lutz B (2008) The endocannabinoid system: emotion, learning and addiction. Addict Biol 13:196-212.
Jeong WI, Osei-Hyiaman D, Park O, Liu J, Bátkai S, Mukhopadhyay P, Horiguchi N, Harvey-White J, Marsicano G, Lutz B, Gao B, Kunos G. (2008) Paracrine Activation of Hepatic CB(1) Receptors by stellate cell-derived endocannabinoids mediates alcoholic fatty liver. Cell Metab 7:227-35.
Azad SC, Kurz J, Marsicano G, Lutz B, Zieglgänsberger W, Rammes G. (2008) Activation of CB1 specifically located on GABAergic interneurons inhibits LTD in the lateral amygdala. Learn Mem 15:143-52.
Hansen HH, Krutz B, Sifringer M, Stefovska V, Bittigau P, Pragst F, Marsicano, G, Lutz B, Ikonomidou C. Cannabinoids enhance susceptibility of immature brain to ethanol neurotoxicity. Ann Neurol. 2007 Dec 7 [Epub ahead of print]
Steiner MA, Marsicano G, Nestler EJ, Holsboer F, Lutz B, Wotjak CT (2008) Antidepressant-like behavioral effects of impaired cannabinoid receptor type 1 signaling coincide with exaggerated corticosterone secretion in mice. Psychoneuroendocrinology 33:54-67.
Moreira FA, Kaiser N, Monory K, Lutz B (2008) Reduced anxiety-like behaviour induced by genetic and pharmacological inhibition of the endocannabinoid-degrading enzyme fatty acid amide hydrolase (FAAH) is mediated by CB1 receptors. Neuropharmacology 54:141-50.
Moreira FA (2007) Serotonin, the prefrontal cortex, and the antidepressant-like effect of cannabinoids. J Neurosci 27:13369-70. (Review)
Lutz B (2007) The endocannabinoid system and extinction learning. Mol Neurobiol 36:92-101.
Schneider M, Spanagel R, Zhang SJ, Bading H, Klugmann M (2007) Adeno-associated virus (AAV)-mediated suppression of Ca2+/calmodulin kinase IV activity in the nucleus accumbens modulates emotional behaviour in mice BMC Neurosci 8:105
Monory K, Blaudzun H, Massa F, Kaiser N, Lemberger T, Schütz G, Wotjak CT, Lutz B, Marsicano G (2007) Genetic dissection of behavioural and autonomic effects of Delta(9)-tetrahydrocannabinol in mice. PLoS Biol 5:e269.
Izzo AA, Aviello G, Petrosino S, Orlando P, Marsicano G, Lutz B, Borrelli F, Capasso R, Nigam S, Capasso F, Di Marzo V (2007) Increased endocannabinoid levels reduce the development of precancerous lesions in the mouse colon. J Mol Med 86:89-98.
Yuece B, Sibaev A, Broedl UC, Marsicano G, Goke B, Lutz B, Allescher HD, Storr M (2007)Cannabinoid type 1 receptor modulates intestinal propulsion by an attenuation of intestinal motor responses within the myenteric part of the peristaltic reflex. Neurogastroenterol Motil 19:744-53.
Steiner MA, Wanisch K, Monory K, Marsicano G, Borroni E, Bachli H, Holsboer F, Lutz B, Wotjak CT. Impaired cannabinoid receptor type 1 signaling interferes with stress-coping behavior in mice. Pharmacogenomics J. 2007 Aug 7; [Epub ahead of print]
Corbille AG, Valjent E, Marsicano G, Ledent C, Lutz B, Herve D, Girault JA (2007) Role of cannabinoid type 1 receptors in locomotor activity and striatal signaling in response to psychostimulants. J Neurosci 27:6937-47.
Agarwal N, Pacher P, Tegeder I, Amaya F, Constantin CE, Brenner GJ, Rubino T, Michalski CW, Marsicano G, Monory K, Mackie K, Marian C, Batkai S, Parolaro D, Fischer MJ, Reeh P, Kunos G, Kress M, Lutz B, Woolf CJ, Kuner R (2007) Cannabinoids mediate analgesia largely via peripheral type 1 cannabinoid receptors in nociceptors. Nat Neurosci 10:870-9.
Aguado T, Romero E, Monory K, Palazuelos J, Sendtner M, Marsicano G, Lutz B, Guzman M, Galve-Roperh I (2007) The CB1 cannabinoid receptor mediates excitotoxicity-induced neural progenitor proliferation and neurogenesis. J Biol Chem 282:23892-8.
Berghuis P, Rajnicek AM, Morozov YM, Ross RA, Mulder J, Gabriella M, Urbán GM, Monory K, Marsicano G, Matteoli M, Canty A, Irving AJ, Katona I, Yanagawa Y, Rakic P, Lutz B, Ken Mackie K, Harkany T (2007) Hardwiring the brain: endocannabinoids control axon guidance. Science 316:1212-16
Maresz K, Pryce G, Ponomarev ED, Marsicano G, Croxford JL, Shriver LP, Ledent C, Cheng X, Carrier EJ, Mann MK, Giovannoni G, Pertwee RG, Yamamura T, Buckley NE, Hillard CJ, Lutz B, Baker D, Dittel BN. (2007) Direct suppression of CNS autoimmune inflammation via the cannabinoid receptor CB1 on neurons and CB2 on autoreactive T cells. Nat Med 13(4):492-7.
Häring M, Marsicano G, Lutz B, Monory K. (2007) Identification of the cannabinoid receptor type 1 in serotonergic cells of raphe nuclei in mice. Neuroscience 146:1212-9.
Marsch R, Foeller E, Rammes G, Bunck M, Kössl M, Holsboer F, Zieglgänsberger W, Landgraf R, Lutz B, Wotjak CT (2007) Reduced anxiety, conditioned fear, and hippocampal long-term potentiation in transient receptor potential vanilloid type 1 receptor-deficient mice. J Neurosci 27:832-9.
Deshmukh S, Onozuka K, Bender KJ, Bender VA, Lutz B, Mackie K, Feldman DE (2007) Postnatal development of cannabinoid receptor type 1 expression in rodent somatosensory cortex. Neuroscience 2007 145:279-87.
Brenz Verca MS, Weber P, Mayer C, Graf C, Refojo D, Kuhn R, Grummt I, Lutz B (2007) Development of a species-specific RNA polymerase I-based shRNA expression vector. Nucl Acids Res 35:e10.
Cota D, Steiner MA, Marsicano G, Cervino C, Herman JP, Grubler Y, Stalla J, Pasquali R, Lutz B, Stalla GK, Pagotto U (2007) Requirement of cannabinoid receptor type 1 for the basal modulation of hypothalamic-pituitary-adrenal axis formation. Endocrinology 148:1574-81.
Steiner M, Lutz B (2006) Physiologie und Pharmakologie des Endocannabinoid-Systems. Ed. Schusdziarra V. Das Endocannabinoid-System. UNI-MED Verlag Bremen. pp 11-24.
Steiner M, Lutz B (2006) Endocannabinoid-System und zentrales Nervensystem. Ed. Schusdziarra V. Das Endocannabinoid-System. UNI-MED Verlag Bremen. pp 25-44
Melis M, Pillolla G, Bisogno T, Minassi A, Petrosino S, Perra S, Muntoni AL, MD, Lutz B, PhD, Gessa GL, Marsicano G, Di Marzo V, Pistis M (2006) Protective activation of the endocannabinoid system during Ischemia in dopamine neurons. Neurobiol Dis 24:15-27.
Barad M, Gean PW, Lutz B (2006) The role of the amygdala in the extinction of conditioned fear. Biol Psychiatry 60:322-328.
Monory K, Massa F, Egertova M, Eder M, Blaudzun H, Westenbroek R, Kelsch W, Jacob W, Marsch R, Ekker M, Long J, Rubenstein JL, Goebbels S, Nave KA, During M, Klugmann M, Wolfel B, Dodt HU, Zieglgänsberger W, Wotjak CT, Mackie K, Elphick MR, Marsicano G, Lutz B. (2006) The endocannabinoid system controls key epileptogenic circuits in the hippocampus. Neuron 51:455-66.
Domenici MR, Azad SC, Schierloh A, Wotjak CT, Dodt HU, Marsicano G, Zieglgänsberger W, Lutz B, Rammes G (2006) Evidence for the control of excitatory synaptic transmission by activation of cannabinoid receptor type 1 (CB1) located on presynaptic terminals of principal neurons in the cortex. J Neurosci 26:5794-9.
Pagotto U, Cervino C, Vicennati V, Marsicano G, Lutz B, Pasquali R (2006) How many sites of action for endocannabinoids to control energy metabolism? Int J Obes (Lond) 30 (Suppl 1):S39-43.
Kamprath C, Marsicano G, Tang J, Monory K, Bisogno T, Di Marzo V, Lutz B, Wotjak CT (2006) Cannabinoid CB1 receptor mediates fear extinction via habituation-like processes. J Neurosci 26:6677-86.
Marsicano G, Lutz B (2006) Neuromodulatory functions of the endocannabinoid system, J Endocrinol Invest 29(3 Suppl):27-46.
Massa F, Monory K. (2006) Endocannabinoids and the gastrointestinal tract. J Endocrinol Invest 29(3 Suppl):47-57.
Sibaev A, Massa F, Yuce B, Marsicano G, Lehr HA, Lutz B, Goke B, Allescher HD, Storr M (2006) CB1 and TRPV1 receptors mediate protective effects on colonic electrophysiological properties in mice. J Mol Med 84(6):513-20.
Massa F, Sibaev A, Marsicano G, Blauzun, Storr M, Lutz B (2006) Vanilloid receptor (TRPV1)-deficient mice show increased susceptibility to dinitrobenzene sulfonic acid-induced colitis. J Mol Med 84:142-6.
Pagotto U, Marsicano G, Cota D, Lutz B, Pasquali R (2006) The emerging role of the endocannabinoid system in endocrine regulation and energy balance. Endocr Rev 27:73-100.
Aguado T, Palazuelos J, Monory K, Stella N, Cravatt B, Lutz B, Marsicano G, Kokaia Z, Guzman, M, Galve-Roperh I (2006) The endocannabinoid system promotes astroglial differentiation b acting on neural progenitor cells. J Neurosci 26:1551-1561.
Obradovic D, Gronemeyer H, Lutz B, ReinT (2006) Antagonizing actions of vitamin D3 on glucocorticoid functions in hippocampal cells. J Neurochem 96:500-509.
Massa F, Storr M, Lutz B (2005) The endocannabinoid system in the physiology and pathophysiology of the gastrointestinal tract. J Mol Med 83:944-54.
Aguado T, Monory K, Palazuelos J, Stella N, Cravatt B, Lutz B, Marsicano G, Kokaia Z, Guzman M, Galve-Roperh I (2005) The endocannabinoid system drives neural progenitor proliferation. FASEB J. 19:1704-6.
Capasso R, Matias I, Lutz B, Borrelli F, Capasso F, Marsicano G, Mascolo N, Petrosino S, Monory K, Valenti M, Di Marzo V, Izzo AA (2005) Fatty acid amide hydrolase controls mouse intestinal motility in vivo. Gastroenterology 129:941-51.
Monory K, Lutz B (2005) Pain killer without a high. Nat Med 11:378-379. (Commentary)
Hölter SM, Kallnik M, Wurst W, Marsicano G, Lutz B, Wotjak CT (2005) Cannabinoid CB1 receptor is dispensable for memory extinction in an appetitively-motivated learning task. Eur J Pharmacol 510:69-74.
Hermann H, Lutz B (2005) Coexpression of the cannabinoid receptor type 1 with the corticotropin-releasing hormone receptor type 1 in distinct regions of the adult mouse forebrain. Neurosci Lett 375:13-18.
Bayatti N, Hermann H, Lutz B, Behl C(2005) CRH-mediated induction of BDNF expression is inhibited by the activation of the cannabinoid system. Endocrinology 146:1205-1213.
Melis M, Perra S, Muntoni AL, Pillolla G, Lutz B, Marsicano G, Di Marzo V, Gessa GL, Pistis M (2004) Prefrontal cortex stimulation induces 2-arachidonoyl-glycerol-mediated suppression of excitation in dopamine neurons. J Neurosci 24:107070-10715.
Azad SC, Monory K, Marsicano G, Cravatt BF, Lutz B, Zieglgänsberger W and Rammes G (2004). Circuitry for associative plasticity in the amygdala involves endocannabinoid signaling. J Neurosci 24:9953-9961.
Sanchis-Segura C, Cline BH, Marsicano G, Lutz B, Spanagel R (2004) Reduce sensitivity to reward in CB1 knockout mice. Psychopharmacology 176:223-232.
Lutz B (2004) On-demand activation of the endocannabinoid system in the control of neuronal excitability and epileptiform seizures. Biochem Pharm 68:1691-1998. (Review)
Zhang Z, Hofmann C, Casanova E, Schütz G, Lutz B (2004) Generation of a conditional allele of the CBP gene in mouse. Genesis 40:82-89.
Cannich A, Wotjak C, Kamprath C, Lutz B, Marsicano G (2004). CB1 cannabinoid receptors modulate kinase and phosphatase activity during extinction of conditioned fear in mice. Learning & Memory, Learning & Memory 11:625-632.
Massa F, Marsicano G, Hermann H, Cannich A, Monory K, Cravatt BF, Ferri G-L, Sibaev A, Storr M, Lutz B (2004) The endogenous cannabinoid system protects against colonic inflammation. J Clin Invest 113:1202-1209.
Sitz JH, Tigges M, Baumgärtel K, Khaspekov LG, Lutz B (2004) Dyrk1A potentiates steroid hormone-induced transcription via the chromatin remodeling factor Arip4. Mol Cell Biol 24:5821-5834.
Khaspekov LG, Brenz Verca MS, Frumkina LE, Hermann H, Marsicano G, Lutz B (2004) Involvement of brain-derived neurotrophic factor in cannabinoid receptor-dependent protection against excitotoxicity. Eur J Neurosci 19:1691-1698.
Storr M, Sibaev A, Marsicano G, Lutz B, Schusdziarra V, Timmermans JP, Allescher HD. (2004) Cannabinoid receptor type 1 modulates excitatory and inhibitory neurotransmission in mouse colon. Am J Physiol Gastrointest Liver Physiol 286:G110-G117.
Marsicano G, Goodenough S, Monory K, Hermann H, Eder M, Cannich A, Azad SC, Grazia Cascio M, Ortega Gutiérrez S, van der Stelt M, Luz López-Rodriguez M, Casanova E, Schütz G, Zieglgänsberger W, Di Marzo V, Behl C, Lutz B (2003) CB1 cannabinoid receptors mediate on-demand defense against excitotoxicity. Science 302:84-88.
Marsicano G, Cota D, Stalla GK, Pasquali R, Pagotto U, Lutz B (2003) Cannabinoids in energy balance and prospectives in the therapy of obesity. Curr Med Chem CNS Agents 3:81-87. (Review)
Izzo AA, Capasso F, Costagliola A, Bisogno T, Marsicano G, Ligresti A, Matias I, Capasso R, Pinto L, Borrelli F, Cecio A, Lutz B, Mascolo N, Di Marzo V. (2003) An endogenous cannabinoid tone attenuates cholera toxin-induced fluid accumulation in mice. Gastroenterology 125:765-774.
Cota D, Marsicano G, Tschöp M, Grübler Y, Flachskamm C, Schubert M, Auer D, Thöne-Reinecke C, Ortmann S, Cervino C, Linthorst A, Pasquali R, Lutz B, Stalla GK, Pagotto U (2003) Decreased fat mass in mice deficient for cannabinoid receptor 1 is due to decreased orexigenic drive and impaired adipocyte differentiation. J Clin Invest 112:423-431.
Cota D, Marsicano G, Lutz B, Vicennati V, Stalla GK, Pasquali R, Pagotto U (2003) The endogenous cannabinoid system as a modulator of food intake. Int J Obes Relat Metab Disord, 27:289-301. (Review)
Hermann H, De Petrocellis L, Bisogno T, Moriello TA, Lutz B, Di Marzo V (2003) Dual action of a cannabinoid receptor agonist on capsaicin-induced increase of intracellular Ca2+ in cells co-expressing cannabinoid CB1 and vanilloid VR1 receptors. Cell Mol Life Sci 60:607-616.
Azad SC, Eder M, Marsicano G, Lutz B, Zieglgänsberger W, Rammes G (2003) Activation of the cannabinoid receptor type 1 decreases glutamatergic and GABAergic synaptic transmission in the lateral amygdala of the mouse. Learn Mem 10:116-128.
Lutz, B (2003) Cannabinoids in memory processing. Acta Phytotherapeutica 3(1):15-21.
Marsicano G, Wotjak CW, Azad SC, Bisogno T, Rammes G, Song T, Hofmann C, Zieglgänsberger W, Di Marzo V, Lutz B (2002) The endogenous cannabinoid system controls extinction of aversive memories. Nature 418:530-535.
Lutz B (2002) Molecular biology of cannabinoid receptors. Prostaglandins Leukot Essent Fatty Acids 66:123-142. (Review)
Zhang Z, Lutz B (2002) Cre recombinase-mediated inversion using lox66 and lox71: Method to introduce conditional point mutations into the CREB-binding protein (CBP). Nucleic Acids Res 30:E90-0.
Marsicano G, Moosmann B, Hermann H, Behl+ C, Lutz+ B (2002) Neuroprotective properties of cannabinoids against oxidative stress: role of the cannabinoid receptor CB1. J Neurochem 80:448-456. (+equal contributions)
Hermann H, Marsicano G, Lutz B (2002) Coexpression of the cannabinoid receptor type 1 with dopamine and serotonin receptors in distinct neuronal subpopulations of the adult mouse forebrain. Neuroscience 109:451-460.
Pagotto U, Marsicano G, Fezza F, Theodoropoulou M, Grübler Y, Stalla J, Arzberger T, Milone A, Losa M, Di Marzo V, Stalla+ G, Lutz+ B (2001) Normal human pituitary gland and pituitary adenomas express cannabinoid receptor type 1 and synthesize endogenous cannabinoids. First evidence for a direct role of cannabinoids on hormone modulation at human pituitary level. J Clin Endocrinol Metab 86:2687-2696 (+equal contributions).
Azad SC, Marsicano G, Eberlein I, Putzke J, Zieglgänsberger W, Spanagel R, Lutz B (2001) Differential role of the nitric oxide pathway on ?9-THC-induced central nervous system effects in the mouse. Eur J Neurosci 13:561-568.
Rammes G, Steckler T, Kresse A, Schütz G, Zieglgänsberger W, Lutz B (2000) Synaptic plasticity and fear conditioning in mice expressing dominant-negative cAMP response element-binding protein (CREB) in forebrain. Eur J Neurosci 12:2534-2546.
Ong WY, Lim HM, Lim TM, Lutz B (2000) Kainate-induced neuronal injury leads to persistent phosphorylation of cAMP response element-binding protein in glial and endothelial cells in the hippocampus. Exp Brain Res 131:178-186.
Klostermann A, Lutz B, Gertler F, Behl C (2000) The orthologous human and murine semaphorin 6A-1 proteins (SEMA6A-1/Sema6A-1) bind to the enabled/vasodilator-stimulated phosphoprotein-like protein (EVL) via a novel carboxyl-terminal zyxin-like domain. J Biol Chem 275:39647-53.
Marsicano G, Lutz B (1999) Expression of the cannabinoid receptor CB1 in distinct neuronal subpopulations in the adult mouse forebrain. Eur J Neurosci 11:4213-4225.
Lutz B, Schmid W, Niehrs C, Schütz G (1999) Essential role of CREB family proteins during Xenopus embryogenesis. Mech Dev 88:55-66.